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21. U.S. Actions Can Help Keep Global Polio Eradication Strategy on Track

Author:
Nellie Bristol
Publication Date:
07-2015
Content Type:
Working Paper
Institution:
Center for Strategic and International Studies (CSIS)
Abstract:
The Global Polio Eradication Initiative (GPEI) in April 2013 unveiled an ambitious six-year strategy aimed at finally ending polio worldwide. The four-pronged approach called for stopping transmission in the remaining polio endemic countries while also eliminating rare but paralyzing vaccine-related polio. It outlined plans to ensure proper laboratory and health facility containment of poliovirus as eradication neared. Lastly, the Polio Eradication & Endgame Strategic Plan 2013–2018 urged countries, donors, and international partners to begin planning for the transition of polio program resources to country heath systems and other health initiatives. The drive to eradicate polio is at a pivotal point. The number of cases is down globally compared to last year. Polio programs in both Nigeria and Pakistan are moving in a positive direction while progress in Afghanistan is holding steady. A successful move to bivalent OPV would greatly reduce the number of polio cases caused by vaccine viruses and set the stage for an eventual worldwide switch to IPV. But extraordinary efforts still are required to reach the endgame strategy’s goals.
Topic:
Health, Infectious Diseases, and Health Care Policy

22. Contagion Exposure and Protection Technology

Author:
Deigo Cerdeiro
Publication Date:
05-2015
Content Type:
Working Paper
Institution:
Institute for New Economic Thinking (INET)
Abstract:
People adopt diverse measures to protect from contagion. I propose a taxonomy of protection technologies, and present a model to study the implications of the technology on the prevalence of infections and on welfare at different levels of exposure. People adopt diverse measures to protect from contagion. I propose a taxonomy of protection technologies, and present a model to study the implications of the technology on the prevalence of infections and on welfare at different levels of exposure. I find that the effect of aggregate exposure on prevalence and on protection inefficiencies depends crucially on the characteristics of the available protection technology. For example, under certain conditions the existence of a vaccine will lead to lower infection rates and smaller welfare costs of decentralization as the society becomes denser. I discuss the implications for disease eradication, the equilibrium consequences of antigenic drift, the desirability of interventions in the absence of universal vaccines, and coordination failures in protection.
Topic:
Health, Science and Technology, Infectious Diseases, and Medicine
Political Geography:
Global Focus

23. Economic Analysis of Duck Production Household Farm Level in the Context of Highly Pathogenic Avian Influenza Subtype H5N1 in the Red River Delta, Vietnam

Author:
Chinh C. Tran and John F. Yanagida
Publication Date:
10-2014
Content Type:
Working Paper
Institution:
East-West Center
Abstract:
Occurrence of the Highly Pathogenic Avian Influenza subtype H5N1 usually results in the complete loss of the producer's entire flock due to high mortality rate and stamping out conducted to contain the virus. This study explores the expected economic impacts of HPAI H5N1 on smallholder duck producers in the Red River Delta of Vietnam. A conceptual model is developed to describe how a producer responds at each week of duck production to maximize profit and evaluate expected profits/losses of the producer in light of HPAI H5N1. The results suggests that in the case of no disease occurrence, the optimal time to sell ducks is at week 10 of the production cycle when ducks reach the age of 8 weeks. Maximum profit gained is US$805 for a producer with an average flock size of 794 ducks. However, the producer would suffer serious losses once the disease occurs. The expected investment loss is far higher than the maximum profit received at each production cycle and is estimated to be 3 times higher.
Topic:
Economics, Health, Infectious Diseases, and Food
Political Geography:
Vietnam

24. Perceived Risk of Avian Influenza in Poultry Varies with Urbanization in Vietnam

Author:
Jefferson Fox, Melissa L. Finucane, Sumeet Saksena, Nghiem Tuyen, James H. Spencer, Nguyen Lam, Trinh Dinh Thau, Tran Duc Vien, and Nancy D. Lewis
Publication Date:
10-2014
Content Type:
Working Paper
Institution:
East-West Center
Abstract:
Highly pathogenic avian influenza (HPAI) is an important public health concern because of its potential to cause widespread morbidity and mortality in humans and poultry and associated devastating economic losses. In this study we examined how perceptions of and response to the risk of HPAI in poultry vary across communes/wards in the north of Vietnam at different levels of urbanization (rural, transitional, urban). We conducted a quantitative household survey with 1073 respondents. Results suggested that the perceived risk of HPAI in poultry was highest in transitional and rural settings. Respondents in these settings were more likely than respondents in urban settings to agree that the process of change (in urbanization, agricultural practices, or natural habitat) increased the likelihood of an outbreak of HPAI in poultry. Compared with others, respondents in transitional areas reported that they do less planning and perceive vaccines to be more effective, while respondents in rural areas reported less perceived ability to separate infected poultry from others. We also found that the inability to respond is not necessarily because of an inability to perceive change but because, rapid and extensive change poses different challenges for poultry management as communes move from rural to transitional to urban settings. Our results suggest that public and animal health campaigns could be tailored in a way that recognizes the needs of poultry raisers in different settings.
Topic:
Health, Infectious Diseases, and Urbanization
Political Geography:
Asia and Vietnam

25. Role of Urbanization, Land-Use Diversity, and Livestock Intensification in Zoonotic Emerging Infectious Diseases

Author:
Jefferson Fox, Duong Nong, Miguel Castrence, James Spencer, Sumeet Saksena, Nguyen Lam, Tran Duc Vien, Michael Epprecht, Chinh Tran, Melissa Finucane, and Bruce Wilco
Publication Date:
10-2014
Content Type:
Working Paper
Institution:
East-West Center
Abstract:
Emerging infectious diseases (EIDs) continue to significantly threaten human and animal health. While there has been some progress in identifying underlying proximal driving forces and causal mechanisms of disease emergence, the role of distal factors is most poorly understood. This article focuses on analyzing the statistical association between highly pathogenic avian influenza (HPAI) H5N1 and urbanization, land-use diversity and poultry intensification. A special form of the urban transition—peri-urbanization—was hypothesized as being associated with 'hot-spots' of disease emergence. Novel metrics were used to characterize these distal risk factors. Our models, which combined these newly proposed risk factors with previously known natural and human risk factors, had a far higher predictive performance compared to published models for the first two epidemiological waves in Viet Nam. We found that when relevant risk factors are taken into account, urbanization is generally not a significant independent risk factor. However, urbanization spatially combines other risk factors leading to peri-urban places being the most likely 'hot-spots'. The work highlights that peri-urban areas have highest levels of chicken density, duck and geese flock size diversity, fraction of land under rice, fraction of land under aquaculture compared to rural and urban areas. Land-use diversity, which has previously never been studied in the context of HPAI H5N1, was found to be a significant risk factor. Places where intensive and extensive forms of poultry production are collocated were found to be at greater risk
Topic:
Health, Infectious Diseases, and Urbanization
Political Geography:
United States and Asia

26. Improving Maternal, Neonatal, and Child Health in Ghana

Author:
Katherine E. Bliss and Cathryn Streifel
Publication Date:
11-2014
Content Type:
Working Paper
Institution:
Center for Strategic and International Studies (CSIS)
Abstract:
In June 2014, a small team from the CSIS Global Health Policy Center traveled to Ghana to examine U.S. bilateral support for maternal, neonatal, and child health (MNCH). The purpose of the trip was to plan a return visit with a delegation of U.S. congressional staff in August 2014. Ghana's mixed progress toward meeting Millennium Development Goals (MDG) 4 and 5 related to maternal and child health; its strong relationship on immunizations with Gavi, the Vaccine Alliance; and its longstanding partnership on health with the United States were all reasons we decided to examine the country's MNCH situation. By late July, the acceleration of the Ebola outbreak in West Africa led us to postpone the trip until emergency preparations are not a major focus of the Ghanaian government, the United States, and other partners. Considering the fruitful meetings we had in June, we have captured here some of our initial impressions, observations, and recommendations.
Topic:
Health, Infectious Diseases, and Foreign Aid
Political Geography:
Africa, United States, and Ghana

27. Insecticide Resistance and Malaria A Threat Decades in the Making

Author:
William G. Brogdon, Anthony Fiore, S.P. Kachur, Laurence Slutsker, and Robert A. Wirtz
Publication Date:
12-2014
Content Type:
Working Paper
Institution:
Center for Strategic and International Studies (CSIS)
Abstract:
Insecticide (DDT) use to control malaria was first employed successfully in the antimalaria program in Greece in 1947. By 1951, DDT success in controlling malaria was reported in 22 countries. However, that year also saw the first report of DDT resistance, in Anopheles sacharovi in Greece. By 1954, resistance to DDT among mosquitos was known to be a global problem, documented in Europe, the Americas, Africa, and Asia. The World Health Organization–led Global Malaria Eradication Program (GMEP) began in 1955, when resistance was already pronounced worldwide. Scientists did not identify the underlying biochemical mechanism contributing to insecticide resistance until 1958. By then, insecticide resistance was recognized by many to be a major contributor to the ultimate dismantling of GMEP, given the limited capabilities and knowledge of the time. Consequently, the global focus shifted from malaria “eradication” to malaria “control” in the late 1960s.
Topic:
Environment, Health, and Infectious Diseases
Political Geography:
Africa, Greece, and Asia

28. Transformative Tools for Malaria Elimination

Author:
PATH Malaria Center of Excellence
Publication Date:
12-2014
Content Type:
Working Paper
Institution:
Center for Strategic and International Studies (CSIS)
Abstract:
Over the past 15 years, malaria has gained increased attention and action from the public health community, with researchers, global and national funders, and, most importantly, national governments and communities in endemic areas. Renewed efforts to fight the disease have resulted in an unprecedented 50 percent reduction in malaria deaths in African children since 2000. This progress has been achieved in large part because effective, efficient, and affordable tools emerged as a result of earlier investments in research and development.
Topic:
Health, Human Welfare, Humanitarian Aid, International Cooperation, and Infectious Diseases
Political Geography:
Africa

29. The Danger of Untreatable Malaria Is Real and Present

Author:
Christopher V. Plowe
Publication Date:
12-2014
Content Type:
Working Paper
Institution:
Center for Strategic and International Studies (CSIS)
Abstract:
The malaria parasite is thought to have killed more people throughout human history than any other single cause. Over the last decade, a large increase in resources for combating malaria — with the lion's share coming from U.S. taxpayers — has resulted in dramatic reductions in malaria cases and deaths in many countries. These successes spurred the Bill Melinda Gates Foundation and the World Health Organization (WHO) to call for global eradication of malaria in 2007.
Topic:
Development, Health, Humanitarian Aid, World Health Organization, and Infectious Diseases
Political Geography:
United States

30. Ebola and the Private Sector: Bolstering the response and West African economies

Publication Date:
12-2014
Content Type:
Working Paper
Institution:
Oxfam Publishing
Abstract:
The current Ebola outbreak in West Africa is unprecedented. The increasing number of cases, the poor health infrastructure, the shortage of skills, knowledge and personnel, and the fear surrounding the disease are proving a huge challenge to affected governments and to the international community as they battle to bring the epidemic under control.
Topic:
Disaster Relief, Health, Human Welfare, and Infectious Diseases
Political Geography:
Africa and West Africa